Recombinant Canine Coronaviruses in Dogs, Europe

Coronaviruses of potential recombinant origin with porcine transmissible gastroenteritis virus (TGEV), referred to as a new subtype (IIb) of canine coronavirus (CCoV), were recently identified in dogs in Europe.To assess the distribution of the TGEV-like CCoV subtype, during 2001–2008 we tested fecal samples from dogs with gastroenteritis.Of 1,172 samples, 493 (42.06%) were positive for CCoV.
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CCoV-II was found in 218 samples, and CCoV-I and CCoV-II genotypes were found in 182.Approximately 20% of the samples with CCoV-II had the TGEV-like subtype; detection rates varied according to geographic origin.The highest and lowest rates of prevalence for CCoV-II infection were found in samples from Hungary and Greece (96.
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45%, respectively).Sequence and phylogenetic analyses showed that the CCoV-IIb strains were related to prototype TGEV-like strains in the 5′ and the 3′ ends of the spike protein gene

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